Bonaguro Lab

Bonaguro Lab

Junior Research Group @DZNE Bonn

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A list of all the posts and pages found on the site. For you robots out there is an XML version available for digesting as well.

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Alterations of multiple alveolar macrophage states in chronic obstructive pulmonary disease

Published in BioRxiv, 2020

Recommended citation: Kevin Baßler, Wataru Fujii, Theodore S Kapellos, Arik Horne, Benedikt Reiz, Erika Dudkin, Malte Lücken, Nico Reusch, Collins Osei-Sarpong, Stefanie Warnat-Herresthal, Allon Wagner, Lorenzo Bonaguro, Patrick Günther, Carmen Pizarro, Tina Schreiber, Matthias Becker, Kristian Händler, Christian T Wohnhaas, Florian Baumgartner, Meike Köhler, Heidi Theis, Michael Kraut, Marc H Wadsworth, Travis K Hughes, Humberto JG Ferreira, Jonas Schulte-Schrepping, Emily Hinkley, Ines H Kaltheuner, Matthias Geyer, Christoph Thiele, Alex K Shalek, Andreas Feißt, Daniel Thomas, Henning Dickten, Marc Beyer, Patrick Baum, Nir Yosef, Anna C Aschenbrenner, Thomas Ulas, Jan Hasenauer, Fabian J Theis, Dirk Skowasch, Joachim L Schultze. (2020). "Alterations of multiple alveolar macrophage states in chronic obstructive pulmonary disease" BioRxiv.
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Suppressive myeloid cells are a hallmark of severe COVID-19

Published in MedRxiv, 2020

Recommended citation: Jonas Schulte-Schrepping, Nico Reusch, Daniela Paclik, Kevin Baßler, Stephan Schlickeiser, Bowen Zhang, Benjamin Krämer, Tobias Krammer, Sophia Brumhard, Lorenzo Bonaguro*, Elena De Domenico, Daniel Wendisch, Martin Grasshoff, Theodore S Kapellos, Michael Beckstette, Tal Pecht, Adem Saglam, Oliver Dietrich, Henrik E Mei, Axel R Schulz, Claudia Conrad, Désirée Kunkel, Ehsan Vafadarnejad, Cheng-Jian Xu, Arik Horne, Miriam Herbert, Anna Drews, Charlotte Thibeault, Moritz Pfeiffer, Stefan Hippenstiel, Andreas Hocke, Holger Müller-Redetzky, Katrin-Moira Heim, Felix Machleidt, Alexander Uhrig, Laure Bousquillon de Jarcy, Linda Jürgens, Miriam Stegemann, Christoph R Glösenkamp, Hans-Dieter Volk, Christine Goffinet, Jan Raabe, Kim Melanie Kaiser, Michael To Vinh, Gereon Rieke, Christian Meisel, Thomas Ulas, Matthias Becker, Robert Geffers, Martin Witzenrath, Christian Drosten, Norbert Suttorp, Christof von Kalle, Florian Kurth, Kristian Händler, Joachim L Schultze, Anna C Aschenbrenner, Yang Li, Jacob Nattermann, Birgit Sawitzki, Antoine-Emmanuel Saliba, Leif Erik Sander, Deutsche COVID-19 OMICS Initiative (DeCOI). (2020). "Suppressive myeloid cells are a hallmark of severe COVID-19" MedRxiv.
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Severe COVID-19 is marked by a dysregulated myeloid cell compartment

Published in Cell, 2020

Recommended citation: Jonas Schulte-Schrepping, Nico Reusch, Daniela Paclik, Kevin Baßler, Stephan Schlickeiser, Bowen Zhang, Benjamin Krämer, Tobias Krammer, Sophia Brumhard, Lorenzo Bonaguro*, Elena De Domenico, Daniel Wendisch, Martin Grasshoff, Theodore S Kapellos, Michael Beckstette, Tal Pecht, Adem Saglam, Oliver Dietrich, Henrik E Mei, Axel R Schulz, Claudia Conrad, Désirée Kunkel, Ehsan Vafadarnejad, Cheng-Jian Xu, Arik Horne, Miriam Herbert, Anna Drews, Charlotte Thibeault, Moritz Pfeiffer, Stefan Hippenstiel, Andreas Hocke, Holger Müller-Redetzky, Katrin-Moira Heim, Felix Machleidt, Alexander Uhrig, Laure Bosquillon de Jarcy, Linda Jürgens, Miriam Stegemann, Christoph R Glösenkamp, Hans-Dieter Volk, Christine Goffinet, Markus Landthaler, Emanuel Wyler, Philipp Georg, Maria Schneider, Chantip Dang-Heine, Nick Neuwinger, Kai Kappert, Rudolf Tauber, Victor Corman, Jan Raabe, Kim Melanie Kaiser, Michael To Vinh, Gereon Rieke, Christian Meisel, Thomas Ulas, Matthias Becker, Robert Geffers, Martin Witzenrath, Christian Drosten, Norbert Suttorp, Christof von Kalle, Florian Kurth, Kristian Händler, Joachim L Schultze, Anna C Aschenbrenner, Yang Li, Jacob Nattermann, Birgit Sawitzki, Antoine-Emmanuel Saliba, Leif Erik Sander, Angel Angelov, Robert Bals, Alexander Bartholomäus, Anke Becker, Daniela Bezdan, Ezio Bonifacio, Peer Bork, Thomas Clavel, Maria Colome-Tatche, Andreas Diefenbach, Alexander Dilthey, Nicole Fischer, Konrad Förstner, Julia-Stefanie Frick, Julien Gagneur, Alexander Goesmann, Torsten Hain, Michael Hummel, Stefan Janssen, Jörn Kalinowski, René Kallies, Birte Kehr, Andreas Keller, Sarah Kim-Hellmuth, Christoph Klein, Oliver Kohlbacher, Jan O Korbel, Ingo Kurth, Kerstin Ludwig, Oliwia Makarewicz, Manja Marz, Alice McHardy, Christian Mertes, Markus Nöthen, Peter Nürnberg, Uwe Ohler, Stephan Ossowski, Jörg Overmann, Silke Peter, Klaus Pfeffer, Anna R Poetsch, Alfred Pühler, Nikolaus Rajewsky, Markus Ralser, Olaf Rieß, Stephan Ripke, Ulisses Nunes da Rocha, Philip Rosenstiel, Philipp Schiffer, Eva-Christina Schulte, Alexander Sczyrba, Oliver Stegle, Jens Stoye, Fabian Theis, Janne Vehreschild, Jörg Vogel, Max von Kleist, Andreas Walker, Jörn Walter, Dagmar Wieczorek, John Ziebuhr. (2020). "Severe COVID-19 is marked by a dysregulated myeloid cell compartment" Cell. 182(6)
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CRELD1 modulates homeostasis of the immune system in mice and humans

Published in Nature Immunology, 2020

Recommended citation: Lorenzo Bonaguro, Maren Köhne, Lisa Schmidleithner, Jonas Schulte-Schrepping, Stefanie Warnat-Herresthal, Arik Horne, Paul Kern, Patrick Guenther, Rob Ter Horst, Martin Jaeger, Souad Rahmouni, Michel Georges, Christine S Falk, Yang Li, Elvira Mass, Marc Beyer, Leo AB Joosten, Mihai G Netea, Thomas Ulas, Joachim L Schultze, Anna C Aschenbrenner. (2020). "CRELD1 modulates homeostasis of the immune system in mice and humans" Nature Immunology. 21(12)
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Induction of peri-implantation stage synthetic embryos using reprogramming paradigms in ESCs

Published in BioRxiv, 2021

Recommended citation: Jan Langkabel, Arik Horne, Lorenzo Bonaguro, Tatiana Hesse, Alexej Knaus, Yannick Riedel, Kristian Händler, Kevin Bassler, Nico Reusch, Leon Harootoonovtch Yeghiazarian, Tal Pecht, Anna C Aschenbrenner, Franziska Kaiser, Caroline Kubaczka, Joachim L Schultze, Hubert Schorle. (2021). "Induction of peri-implantation stage synthetic embryos using reprogramming paradigms in ESCs" BioRxiv.
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Neutrophils in COVID-19

Published in Frontiers in Immunology, 2021

Recommended citation: Nico Reusch, Elena De Domenico, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Kevin Baßler, Joachim L Schultze, Anna C Aschenbrenner. (2021). "Neutrophils in COVID-19" Frontiers in Immunology.
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Swarm learning for decentralized and confidential clinical machine learning

Published in Nature, 2021

Recommended citation: Stefanie Warnat-Herresthal, Hartmut Schultze, Krishnaprasad Lingadahalli Shastry, Sathyanarayanan Manamohan, Saikat Mukherjee, Vishesh Garg, Ravi Sarveswara, Kristian Händler, Peter Pickkers, N Ahmad Aziz, Sofia Ktena, Florian Tran, Michael Bitzer, Stephan Ossowski, Nicolas Casadei, Christian Herr, Daniel Petersheim, Uta Behrends, Fabian Kern, Tobias Fehlmann, Philipp Schommers, Clara Lehmann, Max Augustin, Jan Rybniker, Janine Altmüller, Neha Mishra, Joana P Bernardes, Benjamin Krämer, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Elena De Domenico, Christian Siever, Michael Kraut, Milind Desai, Bruno Monnet, Maria Saridaki, Charles Martin Siegel, Anna Drews, Melanie Nuesch-Germano, Heidi Theis, Jan Heyckendorf, Stefan Schreiber, Sarah Kim-Hellmuth, Jacob Nattermann, Dirk Skowasch, Ingo Kurth, Andreas Keller, Robert Bals, Peter Nürnberg, Olaf Rieß, Philip Rosenstiel, Mihai G Netea, Fabian Theis, Sach Mukherjee, Michael Backes, Anna C Aschenbrenner, Thomas Ulas, Monique MB Breteler, Evangelos J Giamarellos-Bourboulis, Matthijs Kox, Matthias Becker, Sorin Cheran, Michael S Woodacre, Eng Lim Goh, Joachim L Schultze. (2021). "Swarm learning for decentralized and confidential clinical machine learning" Nature. 594(7862)
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Creld1 regulates myocardial development and function

Published in Journal of Molecular and Cellular Cardiology, 2021

Recommended citation: Vera Beckert, Sebastian Rassmann, Amir Hossein Kayvanjoo, Christina Klausen, Lorenzo Bonaguro, Dominik Simon Botermann, Melanie Krause, Kristin Moreth, Nadine Spielmann, Patricia da Silva-Buttkus, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabě de Angelis, Kristian Händler, Thomas Ulas, Anna C Aschenbrenner, Elvira Mass, Dagmar Wachten. (2021). "Creld1 regulates myocardial development and function" Journal of Molecular and Cellular Cardiology. 594(7862)
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Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19

Published in Immunity, 2021

Recommended citation: Benjamin Krämer, Rainer Knoll, Lorenzo Bonaguro*, Michael ToVinh, Jan Raabe, Rosario Astaburuaga-García, Jonas Schulte-Schrepping, Kim Melanie Kaiser, Gereon J Rieke, Jenny Bischoff, Malte B Monin, Christoph Hoffmeister, Stefan Schlabe, Elena De Domenico, Nico Reusch, Kristian Händler, Gary Reynolds, Nils Blüthgen, Gudrun Hack, Claudia Finnemann, Hans D Nischalke, Christian P Strassburg, Emily Stephenson, Yapeng Su, Louis Gardner, Dan Yuan, Daniel Chen, Jason Goldman, Philipp Rosenstiel, Susanne V Schmidt, Eicke Latz, Kevin Hrusovsky, Andrew J Ball, Joe M Johnson, Paul-Albert Koenig, Florian I Schmidt, Muzlifah Haniffa, James R Heath, Beate M Kümmerer, Verena Keitel, Björn Jensen, Paula Stubbemann, Florian Kurth, Leif E Sander, Birgit Sawitzki, Janine Altmüller, Angel Angelov, Anna C Aschenbrenner, Robert Bals, Alexander Bartholomäus, Anke Becker, Matthias Becker, Daniela Bezdan, Michael Bitzer, Conny Blumert, Ezio Bonifacio, Peer Bork, Bunk Boyke, Helmut Blum, Nicolas Casadei, Thomas Clavel, Maria Colome-Tatche, Markus Cornberg, Inti Alberto De La Rosa Velázquez, Andreas Diefenbach, Alexander Dilthey, Nicole Fischer, Konrad Förstner, Sören Franzenburg, Julia-Stefanie Frick, Gisela Gabernet, Julien Gagneur, Tina Ganzenmueller, Marie Gauder, Janina Geißert, Alexander Goesmann, Siri Göpel, Adam Grundhoff, Hajo Grundmann, Torsten Hain, Frank Hanses, Ute Hehr, André Heimbach, Marius Hoeper, Friedemann Horn, Daniel Hübschmann, Michael Hummel, Thomas Iftner, Angelika Iftner, Thomas Illig, Stefan Janssen, Jörn Kalinowski, René Kallies, Birte Kehr, Andreas Keller, Oliver T Keppler, Sarah Kim-Hellmuth, Christoph Klein, Michael Knop, Oliver Kohlbacher, Karl Köhrer, Jan Korbel, Peter G Kremsner, Denise Kühnert, Ingo Kurth, Markus Landthaler, Yang Li, Kerstin U Ludwig, Oliwia Makarewicz, Federico Marini, Manja Marz, Alice C McHardy, Christian Mertes, Maximilian Münchhoff, Sven Nahnsen, Markus Nöthen, Francine Ntoumi, Peter Nürnberg, Stephan Ossowski, Jörg Overmann, Silke Peter, Klaus Pfeffer, Isabell Pink, Anna R Poetsch, Ulrike Protzer, Alfred Pühler, Nikolaus Rajewsky, Markus Ralser, Kristin Reiche, Olaf Rieß, Stephan Ripke, Ulisses Nunes da Rocha, Philip Rosenstiel, Antoine-Emmanuel Saliba, Leif Erik Sander, Simone Scheithauer, Philipp Schiffer, Jonathan Schmid-Burgk, Wulf Schneider, Eva-Christina Schulte, Joachim L Schultze, Alexander Sczyrba, Mariam L Sharaf, Yogesh Singh, Michael Sonnabend, Oliver Stegle, Jens Stoye, Fabian Theis, Thomas Ulas, Janne Vehreschild. (2021). "Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19; Immunity. 54(11)
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Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients

Published in Genome Medicine, 2021

Recommended citation: Anna C Aschenbrenner, Maria Mouktaroudi, Benjamin Krämer, Marie Oestreich, Nikolaos Antonakos, Melanie Nuesch-Germano, Konstantina Gkizeli, Lorenzo Bonaguro*, Nico Reusch, Kevin Baßler, Maria Saridaki, Rainer Knoll, Tal Pecht, Theodore S Kapellos, Sarandia Doulou, Charlotte Kroeger, Miriam Herbert, Lisa Holsten, Arik Horne, Ioanna D Gemuend, Nikoletta Rovina, Shobhit Agrawal, Kilian Dahm, Martina van Uelft, Anna Drews, Lena Lenkeit, Niklas Bruse, Jelle Gerretsen, Jannik Gierlich, Matthias Becker, Kristian Haendler, Michael Kraut, Heidi Theis, Simachew Mengiste, Elena De Domenico, Jonas Schulte-Schrepping, Lea Seep, Jan Raabe, Christoph Hoffmeister, Michael ToVinh, Verena Keitel, Gereon Rieke, Valentina Talevi, Dirk Skowasch, N Ahmad Aziz, Peter Pickkers, Frank L van de Veerdonk, Mihai G Netea, Joachim L Schultze, Matthijs Kox, Monique MB Breteler, Jacob Nattermann, Antonia Koutsoukou, Evangelos J Giamarellos-Bourboulis, Thomas Ulas. (2021). "Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients; Genome Medicine. 13
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Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs

Published in Nature Communications, 2021

Recommended citation: Jan Langkabel, Arik Horne, Lorenzo Bonaguro, Lisa Holsten, Tatiana Hesse, Alexej Knaus, Yannick Riedel, Matthias Becker, Kristian Händler, Tarek Elmzzahi, Kevin Bassler, Nico Reusch, Leon Harootoonovtch Yeghiazarian, Tal Pecht, Adem Saglam, Thomas Ulas, Anna C Aschenbrenner, Franziska Kaiser, Caroline Kubaczka, Joachim L Schultze, Hubert Schorle. (2021). "Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs; Nature Communications. 13
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Complement activation induces excessive T cell cytotoxicity in severe COVID-19

Published in Cell, 2022

Recommended citation: Philipp Georg, Rosario Astaburuaga-García, Lorenzo Bonaguro, Sophia Brumhard, Laura Michalick, Lena J Lippert, Tomislav Kostevc, Christiane Gäbel, Maria Schneider, Mathias Streitz, Vadim Demichev, Ioanna Gemünd, Matthias Barone, Pinkus Tober-Lau, Elisa T Helbig, David Hillus, Lev Petrov, Julia Stein, Hannah-Philine Dey, Daniela Paclik, Christina Iwert, Michael Mülleder, Simran Kaur Aulakh, Sonja Djudjaj, Roman D Bülow, Henrik E Mei, Axel R Schulz, Andreas Thiel, Stefan Hippenstiel, Antoine-Emmanuel Saliba, Roland Eils, Irina Lehmann, Marcus A Mall, Sebastian Stricker, Jobst Röhmel, Victor M Corman, Dieter Beule, Emanuel Wyler, Markus Landthaler, Benedikt Obermayer, Saskia von Stillfried, Peter Boor, Münevver Demir, Hans Wesselmann, Norbert Suttorp, Alexander Uhrig, Holger Müller-Redetzky, Jacob Nattermann, Wolfgang M Kuebler, Christian Meisel, Markus Ralser, Joachim L Schultze, Anna C Aschenbrenner, Charlotte Thibeault, Florian Kurth, Leif E Sander, Nils Blüthgen, Birgit Sawitzki. (2022). "Complement activation induces excessive T cell cytotoxicity in severe COVID-19; Cells. 185(3)
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Decoding mechanism of action and susceptibility to drug candidates from integrated transcriptome and chromatin state

Published in BioRxiv, 2022

Recommended citation: Caterina Carraro, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Arik Horne, Marie Oestreich, Stefanie Warnat-Herresthal, Tim Helbing, Michele De Franco, Kristian Händler, Sach Mukherjee, Thomas Ulas, Valentina Gandin, Richard Göttlich, Anna C Aschenbrenner, Joachim L Schultze, Barbara Gatto. (2022). "Decoding mechanism of action and susceptibility to drug candidates from integrated transcriptome and chromatin state; BioRxiv.
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Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation

Published in Frontiers in Immunology, 2022

Recommended citation: Kevin Baßler, Wataru Fujii, Theodore S Kapellos, Erika Dudkin, Nico Reusch, Ari Horne, Benedikt Reiz, Malte D Luecken, Collins Osei-Sarpong, Stefanie Warnat-Herresthal, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Allon Wagner, Patrick Günther, Carmen Pizarro, Tina Schreiber, Rainer Knoll, Lisa Holsten, Charlotte Kröger, Elena De Domenico, Matthias Becker, Kristian Händler, Christian T Wohnhaas, Florian Baumgartner, Meike Köhler, Heidi Theis, Michael Kraut, Marc H Wadsworth, Travis K Hughes, Humberto J Ferreira, Emily Hinkley, Ines H Kaltheuner, Matthias Geyer, Christoph Thiele, Alex K Shalek, Andreas Feißt, Daniel Thomas, Henning Dickten, Marc Beyer, Patrick Baum, Nir Yosef, Anna C Aschenbrenner, Thomas Ulas, Jan Hasenauer, Fabian J Theis, Dirk Skowasch, Joachim L Schultze. (2022). "Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation; Frontiers in Immunology.
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A guide to systems-level immunomics

Published in Nature Immunology, 2022

Recommended citation: Lorenzo Bonaguro, Jonas Schulte-Schrepping, Thomas Ulas, Anna C Aschenbrenner, Marc Beyer, Joachim L Schultze. (2022). "A guide to systems-level immunomics; Nature Immunology. 23(10)
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Human variation in population-wide gene expression data predicts gene perturbation phenotype

Published in iScience, 2022

Recommended citation: Lorenzo Bonaguro, Jonas Schulte-Schrepping, Caterina Carraro, Laura L Sun, Benedikt Reiz, Ioanna Gemünd, Adem Saglam, Souad Rahmouni, Michel Georges, Peer Arts, Alexander Hoischen, Leo AB Joosten, Frank L van de Veerdonk, Mihai G Netea, Kristian Händler, Sach Mukherjee, Thomas Ulas, Joachim L Schultze, Anna C Aschenbrenner. (2022). "Human variation in population-wide gene expression data predicts gene perturbation phenotype; iScience.
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Human variation in population-wide gene expression data predicts gene perturbation phenotype

Published in iScience, 2022

This paper is about fixing template issue #693.

Recommended citation: Lorenzo Bonaguro, Jonas Schulte-Schrepping, Caterina Carraro, Laura L Sun, Benedikt Reiz, Ioanna Gemünd, Adem Saglam, Souad Rahmouni, Michel Georges, Peer Arts, Alexander Hoischen, Leo AB Joosten, Frank L van de Veerdonk, Mihai G Netea, Kristian Händler, Sach Mukherjee, Thomas Ulas, Joachim L Schultze, Anna C Aschenbrenner. (2022). "Human variation in population-wide gene expression data predicts gene perturbation phenotype; iScience.
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Lung T cell response in COVID-19

Published in Frontiers in Immunology, 2023

Recommended citation: Mehrnoush Hadaddzadeh Shakiba, Ioanna Gemünd, Marc Beyer, Lorenzo Bonaguro*. (2023). "Lung T cell response in COVID-19." Frontiers in Immunology. 14.
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Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease

Published in Cell Reports, 2023

Recommended citation: Theodore S Kapellos, Kevin Baßler, Wataru Fujii, Christina Nalkurthi, Anna C Schaar, Lorenzo Bonaguro, Tal Pecht, Izabela Galvao, Shobhit Agrawal, Adem Saglam, Erica Dudkin, Amit Frishberg, Elena de Domenico, Arik Horne, Chantal Donovan, Richard Y Kim, David Gallego-Ortega, Tessa E Gillett, Meshal Ansari, Jonas Schulte-Schrepping, Nina Offermann, Ignazio Antignano, Burcu Sivri, Wenying Lu, Mathew S Eapen, Martina van Uelft, Collins Osei-Sarpong, Maarten van den Berge, Hylke C Donker, Harry JM Groen, Sukhwinder S Sohal, Johanna Klein, Tina Schreiber, Andreas Feißt, Ali Önder Yildirim, Herbert B Schiller, Martijn C Nawijn, Matthias Becker, Kristian Händler, Marc Beyer, Melania Capasso, Thomas Ulas, Jan Hasenauer, Carmen Pizarro, Fabian J Theis, Philip M Hansbro, Dirk Skowasch, Joachim L Schultze. (2023). "Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease." Cell Reports. 42(6).
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Identification of the novel FOXP3-dependent Treg cell transcription factor MEOX1 by high-dimensional analysis of human CD4+ T cells

Published in Frontiers in Immunology, 2023

Recommended citation: Kevin Baßler, Lisa Schmidleithner, Mehrnoush Hadaddzadeh Shakiba, Tarek Elmzzahi, Maren Köhne, Stefan Floess, Rebekka Scholz, Naganari Ohkura, Timothy Sadlon, Kathrin Klee, Anna Neubauer, Shimon Sakaguchi, Simon C Barry, Jochen Huehn, Lorenzo Bonaguro*, Thomas Ulas, Marc Beyer. (2023). "Identification of the novel FOXP3-dependent Treg cell transcription factor MEOX1 by high-dimensional analysis of human CD4+ T cells." Frontiers in Immunology. 14.
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Chromatin accessibility profiling of targeted cell populations with laser capture microdissection coupled to ATAC-seq

Published in Cell Reports Methods, 2023

Recommended citation: Caterina Carraro, Lorenzo Bonaguro, Rachana Srinivasa, Martina van Uelft, Victoria Isakzai, Jonas Schulte-Schrepping, Prerna Gambhir, Tarek Elmzzahi, Jessica V Montgomery, Hannah Hayer, Yuanfang Li, Heidi Theis, Michael Kraut, Krishnaa T Mahbubani, Anna C Aschenbrenner, Ireen König, Eugenio Fava, Hans-Ulrich Fried, Elena De Domenico, Marc Beyer, Adem Saglam, Joachim L Schultze. (2023). "Chromatin accessibility profiling of targeted cell populations with laser capture microdissection coupled to ATAC-seq"." Cell Reports Methods. 3(10).
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Identification of drug candidates targeting monocyte reprogramming in people living with HIV

Published in Frontiers in Immunology, 2023

Recommended citation: Rainer Knoll, Lorenzo Bonaguro, Jéssica C Dos Santos, Stefanie Warnat-Herresthal, Maartje CP Jacobs-Cleophas, Edda Blümel, Nico Reusch, Arik Horne, Miriam Herbert, Melanie Nuesch-Germano, Twan Otten, Wouter A van der Heijden, Lisa van de Wijer, Alex K Shalek, Kristian Händler, Matthias Becker, Marc D Beyer, Mihai G Netea, Leo AB Joosten, Andre JAM van der Ven, Joachim L Schultze, Anna C Aschenbrenner. (2023). "Identification of drug candidates targeting monocyte reprogramming in people living with HIV"." Frontiers in Immunology. 14.
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BBSome-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue

Published in BioRxiv, 2024

Recommended citation: Katharina Sieckmann, Nora Winnerling, Dalila Juliana Silva Ribeiro, Ronja Kardinal, Lisa Maria Steinheuer, Geza Schermann, Christina Klausen, Nelli Blank-Stein, Jonas Schulte-Schrepping, Collins Osei-Sarpong, Mattthias Becker, Lorenzo Bonaguro, Marc Beyer, Kevin Thurley, Helen May-Simera, Jelena Zurkovic, Christoph Thiele, Carmen Ruiz de Almodovar, Elvira Mass, Dagmar Wachten. (2024). "BBSome-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue"." BioRvix.
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Community effort to unravel the complex human neuronal landscape exemplified for the striatum

Published in ResearchSquare, 2024

Recommended citation: Shobhit Agrawal, Rebekka Scholz, Celia Hartmann, Leon Hetzel, Caterina Carraro, Joana Bernardes, Tobias Lautwein, Susanne Reinhardt, Marek Franitza, Janina Fuss, Antje Schulze-Selting, André Heimbach, Thomas Conrad, Elena Buena-Atienza, Maren Buettner, Tarek Elmzzahi, Tal Pacht, Stefan Paulusch, Tassilo Wollenweber, Sabine Kock, Maren Falk-Paulsen, Juliana Roscito, Stefan Czemmel, Netherlands Brain Bank, Matthias Becker, Elena De-Domenico, Lorenzo Bonaguro, Sören Franzenburg, Karl Koehrer, Nicolas Casadei, Kristian Händler, Andreas Dahl, Inge Huitinga, Janine Altmueller, Peter Nuernberg, Ezio Bonifacio, Olaf Rieß, Philip Rosenstiel, Dagmar Wieczorek, Markus Noethen, Fabian Theis, Thomas Ulas, Marc Beyer, Joachim Schultze. (2024). "Community effort to unravel the complex human neuronal landscape exemplified for the striatum." ResearchSquare.
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Cost-Efficient Transcriptomic-Based Drug Screening

Published in Jove, 2024

Recommended citation: Jacqueline Leidner*, Heidi Theis, Michael Kraut, Alice Ragogna, Marc Beyer, Joachim Schultze, Jonas Schulte-Schrepping, Caterina Carraro, Lorenzo Bonaguro*. (2024). "Cost-Efficient Transcriptomic-Based Drug Screening." Jove. 204.
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Unveiling the Power of High-Dimensional Cytometry Data with cyCONDOR

Published in BioRxiv, 2024

Recommended citation: Charlotte Kroeger, Sophie Mueller, Jacqueline Leidner*, Theresa Kroeber, Stefanie Warnat-Herresthal, Jannis B Spintge, Timo Zajac, Aleksej Frolov, Caterina Carraro, Simone Puccio, Joachim L Schultze, Tal Pecht, Marc D Beyer, Lorenzo Bonaguro*. (2024). "Unveiling the Power of High-Dimensional Cytometry Data with cyCONDOR (2024)"." BioRvix.
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Faecal microbial transfer and complex carbohydrates mediate protection against COPD

Published in Gut, 2024

Recommended citation: Kurtis F Budden, Shakti D Shukla, Kate L Bowerman, Annalicia Vaughan, Shaan L Gellatly, David LA Wood, Nancy Lachner, Sobia Idrees, Saima Firdous Rehman, Alen Faiz, Vyoma K Patel, Chantal Donovan, Charlotte A Alemao, Sj Shen, Nadia Amorim, Rajib Majumder, Kanth S Vanka, Jazz Mason, Tatt Jhong Haw, Bree Tillet, Michael Fricker, Simon Keely, Nicole Hansbro, Gabrielle T Belz, Jay Horvat, Thomas Ashhurst, Caryn van Vreden, Helen McGuire, Barbara Fazekas de St Groth, Nicholas JC King, Ben Crossett, Stuart J Cordwell, Lorenzo Bonaguro, Joachim L Schultze, Emma E Hamilton‐Williams, Elizabeth Mann, Samuel C Forster, Matthew A Cooper, Leopoldo N Segal, Sanjay H Chotirmall, Peter Collins, Rayleen Bowman, Kwun M Fong, Ian A Yang, Peter AB Wark, Paul G Dennis, Philip Hugenholtz, Philip M Hansbro. (2024). "Faecal microbial transfer and complex carbohydrates mediate protection against COPD." Gut. 73(5).
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The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation

Published in Cell, 2024

Recommended citation: Rainer Knoll, Elisa T Helbig, Kilian Dahm, Olufemi Bolaji, Frederik Hamm, Oliver Dietrich, Martina van Uelft, Sophie Müller, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Lev Petrov, Benjamin Krämer, Michael Kraut, Paula Stubbemann, Charlotte Thibeault, Sophia Brumhard, Heidi Theis, Gudrun Hack, Elena De Domenico, Jacob Nattermann, Matthias Becker, Marc D Beyer, David Hillus, Philipp Georg, Constantin Loers, Janina Tiedemann, Pinkus Tober-Lau, Lena Lippert, Belén Millet Pascual-Leone, Frank Tacke, Gernot Rohde, Norbert Suttorp, Martin Witzenrath, Antoine-Emmanuel Saliba, Thomas Ulas, Julia K Polansky, Birgit Sawitzki, Leif E Sander, Joachim L Schultze, Anna C Aschenbrenner, Florian Kurth. (2024). "The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation." Cell. 187(16).
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Isogenic patient-derived organoids reveal early neurodevelopmental defects in spinal muscular atrophy initiation

Published in Cell Reports Medicine, 2024

Recommended citation: Tobias Grass, Zeynep Dokuzluoglu, Felix Buchner, Ines Rosignol, Joshua Thomas, Antonio Caldarelli, Anna Dalinskaya, Jutta Becker, Fabian Rost, Michele Marass, Brunhilde Wirth, Marc Beyer, Lorenzo Bonaguro, Natalia Rodriguez-Muela. (2024). "Isogenic patient-derived organoids reveal early neurodevelopmental defects in spinal muscular atrophy initiation." Cell Reports Medicine. 5(8).
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Disease-associated microglia and activation of CD8+ T cells precede neuronal cell loss in a model of hereditary spastic paraplegia

Published in BioRxiv, 2024

Recommended citation: Aleksej Frolov, Hao Huang, Dagmar Schütz, Maren Köhne, Nelli Blank-Stein, Collins Osei-sarpong, Maren Büttner, Tarek Elmzzahi, Mukhran Khundadze, Matthias Becker, Lorenzo Bonaguro, Christian A Hübner, Kristian A Händler, Ralf Stumm, Elvira Mass, Marc Beyer. (2024). "Disease-associated microglia and activation of CD8+ T cells precede neuronal cell loss in a model of hereditary spastic paraplegia"." BioRvix.
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